A team of researchers at Purdue University recently showed that a new technology called biodynamic imaging accurately predicts the effectiveness of chemotherapy treatment for dogs with B-cell lymphoma. Biodynamic imaging measures intracellular motion within living tumor tissue freshly collected by surgical biopsy from a patient with cancer. Distinct patterns of intracellular motion are then correlated with sensitivity or resistance of that cancer to a drug or combination of drugs.
- David D. Nolte, PhD
- John J. Turek, PhD
- Michael O. Childress, DVM
Three key benefits to the findings
- Offers a platform for predicting the effectiveness of cancer chemotherapy drugs before they are given, thus potentially avoiding ineffective, toxic treatments.
- Provides evidence that cancer-bearing pet dogs can be effective animal models in preclinical research involving precision medicine.
- May provide a new method for screening cancer drugs for efficacy before they are entered into clinical trials.