Clinical and Translational Science Award One Health Alliance
Animal Disease Models
Animal Disease Models
Both animals and people develop many of the same diseases. These animal disease models detail the similarities and differences of diseases between species.
We invite COHA members to share additional Animal Disease Models, using the links below.
Canine degenerative myelopathy (DM) is a slowly, progressive adult-onset neurodegenerative disease causing paralysis similar to human amyotrophic lateral sclerosis (ALS – Lou Gehrig’s disease). Canine
Diffuse large B-cell lymphoma (DLBCL) is a hematopoietic tumor of B-cells. It is the most common type of non-Hodgkin lymphoma in both people and dogs, with an annual incidence of 15.5-29.9 per 100,000
Epilepsy is a chronic neurological condition characterized by unpredictable seizures, and it affects both humans and animals. Management of epilepsy is often challenging, especially with Dravet
Equine, Integumentary, Nervous, Chemotherapy, Immunotherapy, Medical, Radiation, Surgery
Ocular squamous cell carcinoma (SCC) is a form of neoplasia (e.g. cancer) affecting the eye of both animals and humans. Ocular SCC is relatively rare in humans, affecting 1 in 1,000,000 people in
Chronic kidney disease (CKD) is reported in 1-3% of cats with an estimated one-third of cats developing CKD in their lifetime. In the US, 15% of adults, 37 million people, have CKD. In both cases, the
Diabetes Mellitus (DM) is not a single disease, but a syndrome characterized by hyperglycemia that result from defects in insulin secretion or insulin sensitivity (in target tissues), or both. Several
Inflammatory bowel disease (IBD) involves chronic inflammation of the gastrointestinal (GI) tract. In humans, there are 2 major forms of IBD: Ulcerative Colitis (UC) and Crohn’s Disease. While both
(myxomatous mitral valve disease, chronic mitral valve disease, degenerative mitral valve disease, mitral insufficiency) Mitral valve disease (MVD) can be congenital (a defect in the valve the patient
Osteosarcoma (OS) is the most common primary bone tumor in both dogs and people. While the disease incidence is relatively low in people (800-1000 cases/year), over 25,000 new cases are diagnosed in
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